Zoology 476 - Lecture Schedule* - Spring 2002

Week Date Topics Readings (Kalthoff)

1

Jan 22

Intro and overview of development

Ch. 1

Jan 24

Fertilization I

Ch. 4 (pp. 75-88)

2

Jan 29

Fertilization II

Ch. 4 (pp. 88-96)

Jan 31

Cleavage I - Yolk distribution and cleavage patterns

Ch. 5 (pp. 98-110)

3

Feb 05

Cleavage II - Control mechanisms

Ch. 5 (pp. 111-123)

Feb 07

Cell fate, potency, and determination I - fate mapping and clonal analysis

Ch. 6 (pp. 124-129)

4

Feb 12

Cell fate, potency, and determination II - fate vs. potency (Roux vs. Driesch)

Ch. 6 (pp. 130-146)

Feb 14

Cloning and genomic equivalence

Ch. 7

5

Feb 19

Cytoplasmic determinants I - classic examples

Ch. 8 (pp. 171-187)

Feb 21

Cytoplasmic determinants II - Experimental analysis

Ch. 8 (pp. 188-195)

6

Feb 26

Axis formation and mesodermal induction in Xenopus I

Ch. 9 (pp. 197-212)

Feb 28

Lecture exam #1 (will cover the first 5 weeks)

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7

Mar 05

Axis formation and mesodermal induction in Xenopus II

Ch. 9 (pp. 213-222)

Mar 07

Gastrulation I

Ch. 10 (pp. 224-234)

8

Mar 12

Gastrulation II

Ch. 10 (pp. 234-250)

Mar 14

Neurulation

Ch. 12 (pp. 279-288)

9

Mar 18-22

SPRING BREAK!

 

10

Mar 26

Neural induction and patterning

Ch. 12 (pp. 289-302)

Mar 28

Ectodermal organs I - neural tube

Ch. 13 (pp. 303-317)

11

Apr 02

Ectodermal organs II - neural crest

Ch. 13 (pp. 317-328)

Apr 04

Ectodermal organs III - placodes, epithelium

Ch. 13 (pp. 329-335)

12

Apr 09

Lecture exam #2 (will cover weeks 6-11)

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Apr 11

Endodermal derivatives, axial and paraxial mesoderm

Ch. 14 (pp. 336-350)

13

Apr 16

Intermediate and lateral plate mesoderm

Ch. 14 (pp. 354-368)

Apr 18

Pattern formation and embryonic fields

Ch. 21

14

Apr 23

Developmental genetics - origin & methods, transcriptional control of development (J. Reiss)

Ch. 15, 16

Apr 25

Pattern formation in Drosophila I

Ch. 22 (pp. 551-564)

15

Apr 30

Pattern formation in Drosophila II

Ch. 22 (pp. 564-588)

May 02

Role of Hox genes in vertebrate development

Ch. 23

16

May 07

Developmental mechanisms of evolutionary change

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May 09

Loose ends and wrap-up

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Finals

May 16

Lecture exam #3 (8:00-9:50 a.m.) (will cover weeks 12-16; also will include some cumulative conceptual material)

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* Subject to change.  I will inform you of major changes in class, and also post them on the course website.