Comparing Different Lipid Compositions of Nano Discs for Function of ASR

Presentation Year

2026

College or Department

College of Natural Resources & Sciences

Short Description of your Research or Creative Project (700 characters or less)

This study uses self-assembled nanodiscs with the target membrane protein being ASR to examine how lipid composition affects its function. Three lipids (DMPC, POPC, and DGDG) were used to form nanodiscs, enabling comparison of their influence on ASR activity. A light-to-dark assay was performed to assess functional response under changing conditions, revealing how each lipid environment supports protein behavior. Dynamic light scattering (DLS) was also used to measure nanodisc size and uniformity, of each lipid composition. Together, these approaches provide insight into how lipid composition impacts membrane protein function.

Permission to Publish Work

Yes

Presentation File Upload

chemistry-webb-riley-203634-4x3.pdf (836.28 KB)

Primary Contact: First Name

Riley

Primary Contact: Last Name

Webb

Primary Contact: Email

rjw112@humboldt.edu

Primary Contact: I am a

Undergraduate Student

Primary Contact: Phone Number

7754503243

Indicate File Dimensions

4'x3'