Breadcrumb
Exploring Cellular Communication Network Factor 3 for Craniofacial Bone Regeneration
Presentation Year
2026
College or Department
College of Natural Resources & Sciences
Short Description of your Research or Creative Project (700 characters or less)
Skeletal stem cells (SSCs) are multipotent cells that generate bone, cartilage, and stromal lineages essential for skeletal repair. CCN3 is a bone-anabolic factor that promotes osteogenesis, but its effects on craniofacial SSCs remain unclear. This study uses flow cytometry to characterize SSC populations in mouse mandible versus long bone, revealing site specific differences in bone cartilage stromal progenitors and other subpopulations. Mandible derived SSCs and MSCs will be isolated, expanded, and treated with CCN3 during osteogenic differentiation. Mineralization will be assessed using Alizarin Red S staining to evaluate osteogenic activity. These findings will provide new insight into the unique biology and therapeutic potential of SSCs within the mandible.
Permission to Publish Work
Yes
Presentation File Upload
Primary Contact: First Name
Priscilla
Primary Contact: Last Name
Gamez
Primary Contact: Email
Pg81@humboldt.edu
Primary Contact: I am a
Graduate Student
Primary Contact: Phone Number
8186753791
Indicate File Dimensions
4'x3'