May 3, 2024 | Digital Showcase | Humboldt Library
All Presenters & Abstracts
CSF1R Inhibition Restores Cognition Following Immunotherapy
Presentation Year: 2022
Patients that undergo CAR T-cell therapy often experience significant side effects, including cognitive decline. We have found that CAR T-cell therapy increases microglial activation and disrupts the myelin sheath that is necessary for saltatory conduction. We seek to understand the long term neurological effects of CAR T-cell therapy and ways to restore cognition in patients undergoing immunotherapy.
Cursing Practices: Transitions, and Rituals
Presentation Year: 2022
The practice of excessive cursing is understood in teens and early adults as a transition into adulthood, by developing code switching skills, and strengthening kinship bonds. However as our world is increasingly digitized and kids find themselves socializing online at an ever increasing rate, taboo language has experienced a shift that is acutely represented within the boundaries of online gaming. Within the borders of popular combat games, a ritual of offensiveness takes cursing and derogatory terms to extreme use over their microphones within “in game chat” features. This poster examines these two cursing practices side by side, allowing participants to analyze how the culture changes.
Cut It Out: Reducing Cesarean Section Rates in Low - Risk First - Time Mothers
Presentation Year: 2022
Cesarean section rates have increased 7-fold from 1965 (4.5%) and are now the nation’s most common operating – room procedure. One in five deliveries is by C – section according to the World Health Organization. A Healthy People 2030 goal, is to reduce this number to 23.6% or less, in low risk, first - time mothers. On my local unit, C - sections hit an all time high and a change is needed to better maternal child outcomes. This projects examines causes for the increase and strategies aimed at reducing the rate, using evidence based practice interventions. The proposed interventions will be targeted at the patient, nursing, and policy level.
Deciphering the Crosstalk within Human Coronary Atherosclerotic Plaque
Presentation Year: 2022
Our project investigates the cross-talk between cells contained within the human coronary atherosclerotic plaque using single-cell technologies.
We mapped the transcriptome of the plaque using 10x transcriptomics and validated our findings with immunohistochemistry and in vitro assays.
We found a predominance of memory T cells suggesting T cells were recruited by antigen engagement with their cognate peptide presented by myeloid cells.
Using in vitro assays, we also found activation of pro-inflammatory and pro-fibrotic pathways in smooth muscle cells after exposure to T cell cytokines.
Our analysis suggests that T cells communicate with myeloid and smooth muscle cells within the plaque
Decreasing Non-Ventilator Hospital Acquired Pneumonia
Presentation Year: 2022
Evidence shows that patients who receive oral care two to four times daily, have their chances of acquiring non-ventilator hospital acquired pneumonia (NV-HAP) decreased by thirty-seven percent. To make this a successful program at our hospital, it would be prudent to create a policy for oral care, train nursing staff and patients of proper oral care and be sure to document in the electronic medical records that oral care has been done. Pneumonia is the number one hospital acquired infection. This information points to a greater need for nurses to perform oral care with patients.
Decreasing patient readmission rates.
Presentation Year: 2022
Patient readmissions within 30 days of discharge not only cost hospitals around 15,000 dollars per incident but also indicate increased mortality rates and worse patient outcomes. Readmissions occur for multiple reasons such as, lack of clear discharge instruction, delayed primary care follow-up, medication issues, or worsening symptoms. Hospitals must take a multidisciplinary approach to addressing this issue. Interventions can be implemented to improve readmission rates, like discharge calls within 48 hours, creation of hospital policy to guide the call, and primary care follow-up within 10 days. With better transition from hospital to primary care, patient readmissions will decrease.
Decreasing patient readmission rates.
Presentation Year: 2022
Patient readmissions within 30 days of discharge not only cost hospitals around 15,000 dollars per incident but also indicate increased mortality rates and worse patient outcomes. Readmissions occur for multiple reasons such as, lack of clear discharge instruction, delayed primary care follow-up, medication issues, or worsening symptoms. Hospitals must take a multidisciplinary approach to addressing this issue. Interventions can be implemented to improve readmission rates, like discharge calls within 48 hours, creation of hospital policy to guide the call, and primary care follow-up within 10 days. With better transition from hospital to primary care, patient readmissions will decrease.
Delirium at end of life: Improving outcomes
Presentation Year: 2022
Terminal delirium is a common condition seen in the hospice setting. Unlike delirium, terminal delirium is usually not reversible. It manifests in the final days or weeks of life and typically causes distress and safety issues for caregivers and patients. Caregivers depend on nurses to educate them on what to expect as their loved one declines. Since terminal delirium is a common occurrence, preparing these caregivers ahead of time is essential. Since terminal agitation can be difficult to assess, organizations may adopt an assessment tool, training nurses on its use. Organizations may also create a nurse-driven protocol that utilizes evidence-based interventions.
Determining Habitat Prferences of Great Egrets through Foraging Rates
Presentation Year: 2022
My research project looked into determining habitat preferences of Great Egrets through foraging rates across Arcata, CA. The three habitats I chose were the Arcata Marsh, Mad River Slough, and Agricultural Fields.
Determining Habitat Prferences of Great Egrets through Foraging Rates
Presentation Year: 2022
My research project looked into determining habitat preferences of Great Egrets through foraging rates across Arcata, CA. The three habitats I chose were the Arcata Marsh, Mad River Slough, and Agricultural Fields.
Determining Iron Concentrations in Seawater using Flow Injection Analysis
Presentation Year: 2022
Iron concentrations in the ocean are important for the health and success of the ocean because it is an essential micronutrient for phytoplankton. However, iron is insoluble in oxygenated seawater and so most iron precipitates and sinks out of the water column. Here we present a method to analyze these low concentrations of iron using flow injection analysis, which we built following Lohan et al. (2006).
Developing a three-dimensional culture system to improve the yield of placental mesenchymal stem cell derived extracellular vesicles
Presentation Year: 2022
In this study, we developed a novel approach to produce placental mesenchymal stem cell derived extracellular vesicles (PMSC-EVs) by utilizing a three-dimensional (3D) cell culture system to potentially use in regenerative medicine applications. CELLine bioreactors are a 3D culture system that is comprised of a polystyrene scaffold, to support a high-density culture, encased in a semipermeable membrane to concentrate all proteins produced by the cells within. When conditioned medium is collected from the compartment PMSC-EVs were produced over an eight-week continuous culture. This method potentially could be used as an alternative to conventional culture methods to improve PMSC-EV yield.
Developing a three-dimensional culture system to improve the yield of placental mesenchymal stem cell derived extracellular vesicles
Presentation Year: 2022
In this study, we developed a novel approach to produce placental mesenchymal stem cell derived extracellular vesicles (PMSC-EVs) by utilizing a three-dimensional (3D) cell culture system to potentially use in regenerative medicine applications. CELLine bioreactors are a 3D culture system that is comprised of a polystyrene scaffold, to support a high-density culture, encased in a semipermeable membrane to concentrate all proteins produced by the cells within. When conditioned medium is collected from the compartment PMSC-EVs were produced over an eight-week continuous culture. This method potentially could be used as an alternative to conventional culture methods to improve PMSC-EV yield.
Digital Dissection Table Demo
Presentation Year: 2022
Check out the library's latest simulation technology, the Digital Dissection Table on the 2nd floor to see how you can interact with high resolution images of functional anatomy and physiology to learn functional anatomy to zoology. Interact to learn biological, kinesiology, medical, and veterinary concepts and details.
Do Dabbling Ducks Forage More in the Morning or at Night?
Presentation Year: 2022
My research project looked at if dabbling ducks forage more in the morning or afternoon. My hypothesis was that they would forage more in the morning than afternoon.
Do Song Sparrows Alter Song in Noisy Natural Environments?
Presentation Year: 2022
This project studied the minimum song note frequencies of Song Sparrows in two different environments. Our results suggest that vocal plasticity arose as an adaptation in response to loud ocean surf, rivers, and wind.
DOC Sampling from Little River and Mad River
Presentation Year: 2022
Dissolved Organic Carbon (DOC) is a fraction of organic carbon with size less than 0.2 micrometers. DOC comes from decomposed plants, bacteria, and algae. Abundant in marine and freshwater systems, it serves as the primary food source for aquatic webs. Generally, rivers have higher concentrations of DOC than the ocean does.
In the estuary, a linear relationship between salinity and DOC indicates that the DOC concentration is fully due to mixing of freshwater and saltwater, and not any significant additional source or removal terms. DOC concentrations decreased from river to ocean. Scholarly articles have pointed this to be normal. Interpretation of data will continue.
DOC Sampling from Little River and Mad River
Presentation Year: 2022
Dissolved Organic Carbon (DOC) is a fraction of organic carbon with size less than 0.2 micrometers. DOC comes from decomposed plants, bacteria, and algae. Abundant in marine and freshwater systems, it serves as the primary food source for aquatic webs. Generally, rivers have higher concentrations of DOC than the ocean does.
In the estuary, a linear relationship between salinity and DOC indicates that the DOC concentration is fully due to mixing of freshwater and saltwater, and not any significant additional source or removal terms. DOC concentrations decreased from river to ocean. Scholarly articles have pointed this to be normal. Interpretation of data will continue.
Drop the Ramp
Presentation Year: 2022
‘Drop The Ramp’ explores creating a landscape of the invasion on Omaha beach on D-day through immersive and intimate screenings.
Sitting in the middle of the larger projection will be a smaller screen showing a war veteran, Frank Devita as he recounts a story never told about storming the beaches of Omaha. Inverting the interview footage to make it a color negative….viewers will need to view through their phones inverting their screens to view Frank as a color positive. This plays on newer generations' relation to war and how we’ve only ever experienced it through screens. It also plays on our relationships with older generations and how their stories might go unappreciated in a modern age
Dunsmuir
Presentation Year: 2022
Dunsmuir is a small town. A film project.